Effect of Hot Fomentation on Plasma HSP70 Levels and Body Temperature

Objective: Our previous study reported that thermal stimulation on thigh muscle in vivo and skeletal muscle-derived cell (SMDC) vitro favorably changed plasma proteins several gene expression, respectively, to prevent atherosclerotic cardiovascular disease (ASCVD). In our experiment using transcriptome, hot caused a slight decrease SMDC density, associated with higher expression of apoptosis-related factors as well HSP70. the present study, HSP70 was compared before after fomentation methods marker heat stress. Furthermore, skin temperature measured assess whether effect local or systemic.
 Method: Subjects were volunteers 3 men 7 women aged 21.8 ± 1.31 (mean SD). Hot consisted four types: towels, packs, red bean bags, sheets. Plasma concentration determined by ELISA. Skin an infrared thermometer.
 Results: significantly reduced loading towels (pre: 18.46 6.55 vs. post: 14.7 6.66 ng / ml, p = 0.011), but not those other types. Thermal stimulated opposite side increased packs bags. There no significant change axillary temperature.
 Conclusion: These results suggest sheets might cause stress at least this condition. bags provide systemic effect. Further evaluation is required for safe effective application ASCVD prevention.